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Netherlands Cohorts Consortium (NCC)

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Putting the strengths of cohort studies together for a long vital and healthy life!

NCC is a unique infrastructure of prospective cohort studies in the Netherlands with a focus on collection, harmonization and pooling of extensive data to address multimorbidity. Through NCC researchers will have access to a diversity of data concerning mental health, physical health, social networks, stress, life style, environment, socio-demographic and economic factors.

We aim to include all population-based and population-representative Dutch cohort studies that provide advanced longitudinal clinical phenotyping and biomedical data for research into the determinants of multimorbidity. NCC brings data and researchers together to perform excellent research into unraveling the complex interplay between biological mechanisms, lifestyle, behavioral, socio-economic and environmental factors. Linkage with CBS-data, PALGA, NKR and other registries will even further strengthen the possibilities for excellent multidisciplinary research.

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Members
The NCC consist of cohort studies covering the whole of the Netherlands, >350.000 participants originate from Amsterdam, Zwolle, Oss, Leiden, Utrecht, Rotterdam, Doetinchem, Zuid-Limburg, and the provinces Groningen, Friesland, Drenthe. The NCC currently includes the cohort studies listed below, but is open for other cohort studies to join in the future.

Data access
Within the NCC we aim to grant access to the infrastructure against data-handling costs. At current, all cohort studies have their own conditions and procedures on data access. Researchers can apply for data according to these individual procedures. Within the near future we will harmonize these procedures, to provide researchers with a one-stop-one-shop possibility to access data of all cohorts included in NCC.

Governance
The NCC is currently coordinated by the Maastricht Study, The Rotterdam Study and Lifelines. This team is responsible for development of the NCC and will monitor the progress. The team is headed by an Executive Board that includes one person per cohort study.

Contact
Miranda T. Schram, Maastricht University Medical Center+, ncc@mumc.nl

NCC and existing Dutch infrastructures
The diverse and longitudinal active data collections of our cohort studies provide the needed basis to multiple existing infrastructures, like BBMRI and Health RI. All individual cohort studies provide their study samples and outcome phenotypes to these infrastructures, thus forming the fundament of such enterprises. The NCC aims to guarantee the foundation on which these infrastructures expect to build.

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